MARINE ROBOTS MAPPING THE PRESENT AND THE PAST: UNRAVELING THE SECRETS OF THE DEEP


Supercharged chimeric antigen receptor T cells in solid tumors

Chimeric antigen receptor (CAR) T cells have demonstrated success in treating select hematological malignancies, but their activity in solid tumors has been comparably modest.Challenges specific to treating solid tumors include trafficking and distribution throughout the tumor site, overcoming the immunosuppressive tumor microenvironment (TME), and

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An adaptive instinctive reaction strategy based on Harris hawks optimization algorithm for numerical optimization problems

An adaptive Harris hawks optimization (HHO) algorithm is proposed to solve the non-linearly constrained optimization problems.The algorithm, namely, instinctive reaction strategy based on HHO (IRSHHO), combines the instinctive reaction strategy (IRS) with the HHO algorithm.In IRSHHO, the increment of step length decreases with the increase in the i

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